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The effect of eight weeks of aerobic training on the serum levels of ALP, ALT, AST and GGT liver enzymes in obese women
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Hasan Naghizadeh   , Zahra Esmaeili , Fatemeh Esmaeili |
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Abstract: (273 Views) |
Introduction: In the new era, obesity is one of the main causes of diseases. Various studies have shown that there is a close relationship between non-alcoholic fatty liver disease and overweight and obesity. The aim of the present study was the effect of eight weeks of aerobic exercise on the serum levels of ALP, ALT, AST and GGT liver enzymes in obese women.
Methods and Materials: The research method was semi-experimental, which was implemented as a pre- and post-test with a control group. For this purpose, 54 obese women with an average age of 36.72±4.11 years and a body mass index of 33.24±3.02 kg/m2 were selected by random sampling and randomly divided into two aerobic exercise groups (27 people) and Control (27 people). Aerobic exercise intervention (55 to 80% vo2max) was implemented for eight weeks and three sessions per week. Blood samples were taken before and 24 hours after the last training session in a 12-hour fasting state to determine the serum concentration of ALP, ALT, AST and GGT liver enzymes. The data were analyzed using the independent and dependent t test at a significance level of α=0.05.
Results: The results showed that following eight weeks of aerobic training, the serum levels of ALP (p=0.021), ALT (p=0.036), AST (p=0.001), GGT (p=0.001) and the AST/ALT ratio (p=0.017) had a significant decrease. In addition, the changes of liver enzymes between the two groups were significant (p<0.05). Also, in the aerobic training group, there were significant changes in increasing vo2max (p=0.019) and decreasing BMI (p=0.022) and body fat percentage (p=0.025).
Conclusion: Eight weeks of aerobic training can possibly reduce the concentration of ALP, ALT, AST and GGT liver enzymes in obese women by improving aerobic capacity and fat metabolism.
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| Keywords: Sports Training, ALP, ALT, AST, GGT |
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Full-Text [PDF 326 kb]
(40 Downloads)
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Type of Study: Research |
Subject:
General
Received: 2024/01/13 | Accepted: 2023/08/23 | Published: 2023/08/23
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