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The effect of denervation on the response of burn wounds to herbal fundermol ointment in rat
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M. شریعتی   , M. خاکساری , G. h. جورسرایی , H. R. جعفری نوه |
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Abstract: (16807 Views) |
| Introduction, T he re a re several r e por t s on the therapeutic effects of herbal
fund errn ol ointment in burn wounds. The aim of this investigation was to evaluate the
effect of denervation on the response of rat burn wounds to this ointment and com pare
its effect with intact animal.
Material and Methods, This experimental study performed on the six groups of adult
male rats . After aneas thesia, small burn was produced on the hind limb of the rats, by
the heated metal device. After aneasthesia, denervation were made on the hind limb by
sci atic and femoral nerve neurotomy. 24 hours after burn, fundermol ointment a nd
sulfadiazine cream were topically appllied wound surface. Area, percentage of wound
healing, angiogenesis growth of ha ir follicules were measured in differen t post-burn
days.
Results, The results show that percentage of wound healing in denervated gro up was
the same as the group cont rol. In the fundermol tre ated denervated group, percentage
of wound healing at days 12, 15, 18, 21, 24, 27, and 30 of post-burn period, was more
than denervated group (P < O.OOI ) . Percentage of wound healing in the silver
slu fadiazine -treated denervated group in 9th to 30th days was highe r th an denerva ted
group (P |
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| Keywords: Wound healing, Denervation, Fundermol ointment, Silver sulfad iazine |
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Full-Text [PDF 1662 kb]
(2212 Downloads)
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Type of Study: Research |
Subject:
General
Received: 2009/01/17 | Published: 2000/11/15
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