Introduction: Neurotrophins like (brain-derived neurotrophic factor,
BDNF) is thought to play an important role in neuronal repair. Recent
experimental evidence noted that BDNF decrease in patients with multiple
sclerosis (MS) and exercise may increases the level of this protein. The
purpose of this study was to evaluate the effect of eight weeks resistance
training on BDNF in female patients with MS. Materials and Methods: Twenty seven female MS patients with 32.4 ± 5.5 years of
old, and expanded disability status scale (EDSS) 1-5, participated in this
study. The subjects were randomly assigned to control group (n=13) or training
group (n=14). Subjects in training group performed selected upper and lower
extremities resistance training with weight-training equipment and rubber bands
3 days a week for 8 weeks. Results: The
results showed that body weight, body mass index, body fat mass and EDSS were
decreased 2.5, 3.4, 5.1 and 27.7 percentage respectively after eight weeks in
training group compared to control group (P
moghadasi M, edalat manesh M A, moeini A, namatollahzadeh M. Effects of eight weeks resistance training on brain derived neurotrophic factor in female patients with multiple sclerosis. Koomesh 1394; 17 (1) :152-159 URL: http://koomeshjournal.semums.ac.ir/article-1-2148-en.html