|
Ethical Consideration in Designing Randomized Clinical Trial on Drug
|
Nematollah Ahangar   |
|
|
|
Abstract: (165 Views) |
| Introduction: Clinical research and the discovery of new drugs are of considerable importance in medical science and health care. By conducting proper preclinical research and then properly designing randomized clinical trials, scientists can develop new drugs to treat diseases and increase the treatment options available to combat a disease. The discovery and development of a new drug or new research on previously approved drugs seeks to achieve an important and significant goal: to find a safe and effective treatment for use in humans. Moreover, they make clear information about any side effects and possible adverse interactions. To ensure these conditions, researchers must use safe and ethical practices throughout their research and experiments. All treaties, agreements and reports related to the observance of ethical principles in clinical research are crystallized in three main features: respect and honoring the research participant, the safety of the intervention and preventing any harm to the research participant and finally Adherence to justice and equality in conducting research. Some of the most important ethical considerations that must be used in a clinical trial involving a drug to achieve the above three goals are: diversity in selecting samples, paying attention to vulnerable population groups, bearing the patient's treatment costs or paying compensation, considerations regarding the informed consent, the use of placebo and related issues, avoiding exploitation in the selection of samples, the transparency of the sponsor/sponsors of the research , and considerations related to the statement of conflict of interest. The purpose of this speech is to familiarize the audience with the upcoming challenges and pay attention to them in the design and conduct of drug-based clinical trials. |
|
| Keywords: Randomized Clinical Trial, Drug, Ethical Consideration |
|
|
Full-Text [PDF 243 kb]
(20 Downloads)
|
Type of Study: Research |
Subject:
General
Received: 2024/03/4 | Accepted: 2023/08/10 | Published: 2023/08/10
|
|
|
|
|
|
|
| Send email to the article author |
|
|
|
| Add your comments about this article |
|
|
|
