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Effect of vitamin B6 on mastalgia: A double blind clinical trial
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Setareh Soltany   , Hamid reza Hemmati , Jafar Alavy Toussy , Enayatollah Gholamaliyan |
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Abstract: (14095 Views) |
| Introduction: Mastalgia is a common but concerning problem for most women referring to medical centers. Vitamins are one of the medical treatments which are used in the treatment of mastalgia. The aim of this study was to evaluate the effect of vitamin B6 on mastalgia.
Materials and Methods: In a randomized double blind clinical trial, patients with mastalgia, who referred to Amir-al-momenin and Kowsar Hospitals in Semnan, Iran, were divided in two study groups. Patients in the case group received vitamin B6 100mg BD for two months and patients in the control group took placebo in a similar route. The patients filled the daily breast pain charts and at the end of the trial, the mean pain score and the number of days with severe pain in the two groups were compared.
Results: Patients (n=126) were evaluated. The mean pain score and the prevalence of severe pain decreased significantly in both groups. In the case group, the mean pain score and the prevalence of severe pain were decreased significantly from the beginning to the end of trial. In both groups, there was a significant reduction of breast pain in the first 5 days. This might be the effect of primary reassurance. No adverse effect of treatment was observed in any of the patients
Conclusion: Vitamin B6 is effective on mastalgia as a safe drug. In addition, primary reassurance has a significant effect on the reduction of the breast pain. |
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| Keywords: Mastodynia, Pyridoxine, Vitamin B6, Pain, Prevalence |
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Full-Text [PDF 626 kb]
(1409 Downloads)
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Type of Study: Research |
Subject:
General
Received: 2016/01/23 | Accepted: 2016/03/14 | Published: 2016/06/23
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