اکثر مکاتبات کومش از طریق ایمیل سایت می باشد. لطفا Spam ایمیل خود را نیز چک نمایید.
   [Home ] [Archive]   [ فارسی ]  
:: ::
Main Menu
Home::
Journal Information::
Articles archive::
For Authors::
Subscription::
Contact us::
Site Facilities::
Webmail::
Editorial Board::
::
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
:: Volume 23, Issue 1 (زمستان 1399) ::
Koomesh 1399, 23(1): 117-123 Back to browse issues page
Evaluation of new method to induce neuritis and comparison its symptoms with current chronic constriction injury method in male rat
A. li Ghanbari , Fatemeh Shahsavan , Hossein Ali Safakhah
Abstract:   (2377 Views)
Introduction: There are various animal models to investigate neuropathic pain which the most usual one is chronic constriction injury method. The aim of the present study was the evaluation of neuropathic pain following chronic spiral suturing around the sciatic nerve without ligation as a new model. Materials and Methods: Thirty Wistar male rats, weighting 180-220 gram randomly were divided into three groups as sham, chronic constriction injury (CCI), and chronic sciatic spiral suturing (CSS). CCI was performed by four loos ligation using catgut chromic suture around sciatic nerve. CSS was performed through spirally suturing of catgut chromic four times around the sciatic nerve without any ligation. In the sham group, muscle and skin were sutured after exposing the nerve. To determine mechanical allodynia and thermal hyperalgesia, Von Frey filaments and plantar test devise were used respectively every four days during three weeks. Results: CCI led to significant mechanical allodynia (P
Keywords: Neuropathic Pain, Mechanical Allodynia, Thermal Hyperalgesia.
Full-Text [PDF 851 kb]   (585 Downloads)    
Type of Study: Research | Subject: General
Received: 2019/12/22 | Accepted: 2020/06/13 | Published: 2021/01/23
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA



XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Ghanbari A L, Shahsavan F, Safakhah H A. Evaluation of new method to induce neuritis and comparison its symptoms with current chronic constriction injury method in male rat. Koomesh 1399; 23 (1) :117-123
URL: http://koomeshjournal.semums.ac.ir/article-1-6093-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 23, Issue 1 (زمستان 1399) Back to browse issues page
کومش Koomesh
Persian site map - English site map - Created in 0.05 seconds with 38 queries by YEKTAWEB 4645