TY - JOUR JF - Koomesh JO - Koomesh VL - 23 IS - 5 PY - 1400 Y1 - 1400/7/01 TI - Effects of co- exposure to heat and psychological stresses on serum levels of testosterone in male rats TT - بررسی اثر مواجهه توأم با استرس گرمایی و روانی بر سطح سرمی تستوسترون در موش‌های صحرایی نر N2 - Introduction: The present study aimed to investigate the effect of co-exposure to heat stress as an environmental stressor and psychological stress on serum levels of testosterone in male rats. Materials and Methods: This study was performed on 40 healthy adult male Wistar rats during a period of 40 days. The rats were evenly and randomly divided into three exposure groups and one control group. The rats in the heat stress group were exposed to 36 ° C and 20% humidity. The rats in psychological stress group was daily exposed to three types of stress: strobe light, cage tilt, and noise. The rats in co-exposure group also experienced both types of heat and psychological stresses.  Then, the level of testosterone was measured in all groups. Results: The results showed that the co-exposure group (4.20 ng/ml ±1.15) had lower hormone levels than the two exposure groups that were separately exposed to heat stress (4.35 ng/ml ± 1.15) and psychological stress (4.98 ng/ml ±1.51) while the level of hormone in the control group was 5.41 ng/ml ± 1.69 (P>0.05). The results of univariate analysis showed that the co-exposure group had the highest difference in hormone levels compared to the control group and the largest effect size. Conclusion: In general, heat and psychological stress can each affect the level of testosterone as one of the components of reproduction system. However, co-exposure to these two types of stressors may lead to more severe effects on the testosterone level. SP - 646 EP - 653 AU - Abbasi Balochkhaneh, Faezeh AU - Farhang Dehghan, Somayeh AU - Haghparast, Abbas AU - Gharari, Noradin AU - Khodakarim Ardakani, Soheila AD - Environmental and Occupational Hazards Control Research Center, School of Public Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran KW - Heat Stress Disorders KW - Physiological Stress KW - Testosterone KW - Rats UR - http://koomeshjournal.semums.ac.ir/article-1-6860-en.html DO - 10.52547/koomesh.23.5.646 ER -