:: جلد 23، شماره 1 - ( زمستان 1399 ) ::
جلد 23 شماره 1 صفحات 71-64 برگشت به فهرست نسخه ها
مقایسه روش‌های پیشرفته جداسازی استخوان در تصاویر رزونانس مغناطیسی مغز، مبتنی بر روش اطلس برای طراحی درمان با تصاویر MR و تصحیح تضعیف تصاویر PET-MR
سمانه مصطفی پور ، حسین عربی
چکیده:   (2673 مشاهده)
هدف: تصاویر رزنانس مغناطیسی (Magnetic Resonance, MR) کاربرد گسترده‌ای در طراحی درمان برای رادیوتراپی و یا اصلاح تضعیف تصاویر PET (Positron Emission Tomography) دارند؛ اما عدم امکان تبدیل مقادیر تصاویر MR به دانسیته الکترونی، ساخت تصاویر مصنوعی را مطرح می‌سازد. از جمله روش‌های مناسب، روش‌های مبتنی بر اطلس است که در این مطالعه، عملکرد دو روش جداسازی استخوان بر مبنای روش اطلس برای تهیه تصاویر CT (Computed Tomography) مصنوعی، از تصاویر MR مغزی، بررسی و مقایسه شده است. مواد و روش‌ها: جداسازی استخوان از تصاویر MR مغزی مربوط به 43 بیمار، با استفاده از دو روش وزن‌دهی محلی بر مبنای اطلس (Atlas-LW (Local weighting atlas-based)) و روش تشخیص الگو بر مبنای اطلس AT-PR (Atlas) registration & Pattern recognition)، انجام شد. صحت این دو روش، برای جداسازی کل استخوان (Bone total) و قسمت قشری (Cortical bone or compact bone) آن با استفاده از پارامترهایی نظیر شباهت Dice (Dice similarity (DSC))، بررسی شد. هم‌چنین صحت مقادیر CT استخراج شده با استفاده از خطای مطلق میانگین (MAE) و خطای جذر میانگین مربعات (RMSE) به‌دست آمد. یافته‌ها: روش Atlas-LW با مقادیر 61/0±79/0=DSC برای استخوان قشری و 03/0±84/0=DSC برای کل استخوان، صحت جداسازی بیش‌تری را نشان داد. این مقادیر برای روش AT-PR به ترتیب از راست به چپ، 8/0±72/0=DSC و 05/0±77/0=DSC بود. نتیجه‌گیری: مقادیر خطای بهتر به‌دست آمده توسط روش Atlas-LW در این مطالعه، نشان‌دهنده توانایی بالقوه این روش به منظور استفاده در طراحی درمان و اصلاح تضعیف تصاویر PET-MR است.  
واژه‌های کلیدی: استخوان، مغز، تصویربرداری تشدید مغناطیسی، برش نگاری نشر پوزیترون، رادیو تراپی
متن کامل [PDF 1121 kb]   (614 دریافت)    
نوع مطالعه: پژوهشي | موضوع مقاله: عمومى
دریافت: 1398/10/30 | پذیرش: 1399/4/22 | انتشار: 1399/10/23
فهرست منابع
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جلد 23، شماره 1 - ( زمستان 1399 ) برگشت به فهرست نسخه ها