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Efect of a controlled diet program on behavioral-emotional disorders in patients with phenylketonuria
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Javad Shahpouri   , Saeideh Karami , Davood Mohammadi , Mohsen Mollamohammadi , Abolfazl Mohammadbeigi |
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Abstract: (3083 Views) |
| Introduction: Phenylketonuria is a disorder due to deficiency of the phenylalanine hydroxylase enzyme. Delay or untreatement would cause impacts on motor-cognitive and individual-social skills. This study aimed to investigate the effect of a controlled diet program on behavioral-emotional disorders in patients with phenylketonuria.
Materials and Methods: In a quasi-experimental study, 60 patients with phenylketonuria referred to Hazrate Masoumeh Hospital in Qom (the seventh largest city in Iran) were studied. The data were collected using parents' strengths and difficulties questionnaire (SDQ) to assess the status of behavioral-emotional disorders in patients by one of parents. Data were collected before and after - a three-months controlled diet- intervention.
Results: The mean of phenylalanine in the patients was 12.81 ± 5.89 mg/dl before intervention and was decreased to 11.88 ± 6.8 mg/dl after intervention and this difference was statistically significant (p=0.018). The most significant effect of intervention was on increase of prosocial behaviors equal to 45%, reduction of conduct problems 38.3%, reduction of hyperactivity-attention deficit problems by 35%, decrease of emotional symptoms by 35% (p |
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| Keywords: Mental disorders, Phenylketonurias, Nutrition Therapy, Child |
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Full-Text [PDF 880 kb]
(828 Downloads)
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Type of Study: Research |
Subject:
General
Received: 2019/01/30 | Accepted: 2019/05/18 | Published: 2020/03/15
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