|
Role of adiponectin in patients with end-stage renal failure
|
Sara Beigrezaei   , Maryam Heidari , Mohammad Reza Tamadon |
|
|
|
Abstract: (5554 Views) |
| Adiponectin is a cytokine produced by the adipose tissue. This collagen-like protein has 244-amino acid and its concentration in plasma of healthy individuals is 5-40 μg / mL. In fact, adiponectin comprises 1% of the total serum protein. Although, adiponectin has anti-inflammatory and anti-atherogenic effects in physiological conditions and plays a key role in lipid and glucose metabolism and energy balance as well. However, in patients with end-stage renal disease, it is not a protector due to the changes in the structure and function, and also is considered as a risk factor. So with regard to the prevalence of atherosclerosis in patients with end stage renal disease, adiponectin may be a marker for indentifying the cardiovascular involvement of these patients. |
|
| Keywords: Adiponectin, Atherosclerosis, Kidney Diseases, Cardiovascular Diseases, Adipose Tissue |
|
|
Full-Text [PDF 575 kb]
(2199 Downloads)
|
Type of Study: Review |
Subject:
General
Received: 2016/09/14 | Accepted: 2017/03/27 | Published: 2017/06/21
|
|
|
|
|
|
