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:: Volume 19, Number 3 ( Summer 2017, 19 (3). 505-711 2017) ::
koomesh 2017, 19(3): 515-522 Back to browse issues page
Role of adiponectin in patients with end-stage renal failure
Sara Beigrezaei, Maryam Heidari, Mohammad Reza Tamadon *
Abstract:   (838 Views)

Adiponectin is a cytokine produced by the adipose tissue. This collagen-like protein has 244-amino acid and its concentration in plasma of healthy individuals is 5-40 μg / mL. In fact, adiponectin comprises 1% of the total serum protein.  Although, adiponectin has anti-inflammatory and anti-atherogenic effects in physiological conditions and plays a key role in lipid and glucose metabolism and energy balance as well. However, in patients with end-stage renal disease, it is not a protector due to the changes in the structure and function, and also is considered as a risk factor. So with regard to the prevalence of atherosclerosis in patients with end stage renal disease, adiponectin may be a marker for indentifying the cardiovascular involvement of these patients.

Keywords: Adiponectin, Atherosclerosis, Kidney Diseases, Cardiovascular Diseases, Adipose Tissue
Full-Text [PDF 575 kb]   (189 Downloads)    
Type of Study: Review | Subject: General
Received: 2016/09/14 | Accepted: 2017/03/27 | Published: 2017/06/21
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Beigrezaei S, Heidari M, Tamadon M R. Role of adiponectin in patients with end-stage renal failure. koomesh. 2017; 19 (3) :515-522
URL: http://koomeshjournal.semums.ac.ir/article-1-3565-en.html
Volume 19, Number 3 ( Summer 2017, 19 (3). 505-711 2017) Back to browse issues page
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