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The effect of topically applied water extract of Rhazya stricta on cutaneous wound healing in rats
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M. خاکساری   , M. E. رضوانی , M. A. سجادی , A. سلیمانی |
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Abstract: (19205 Views) |
| Introduction. Rhazya stricta is used traditionally by kerman selimani tribes , to
accelerte wound healing. The aim of this study was to evaluate the effect of topi cal
application of water extract of Rhazya stricta on cutaneous wound healing and compare
its effect with phenytoin cream.
Materials and Methods. This interventional-experimental study performed on the
three groups of adult male rats. Afte r anaesthesia, full thichness skin of upper dorsal
part of the rats removed in 3 em' area. 24 hours afte r the operation, wound of each
group treated once daily with water extract of R stricta or phenytoin cream (1%).
Control group received no treatment. Wound surface area measured in 0, 4th, 7th,
10th, 13th, and 16th postoperative days. The time required for complete healing was
also recorded.
Results. The results show that wound surface area in R stricta gro up in l Oth day
(60%) and in 13th day (77%) was lower than control group (P < 0.05). Percentage of
wound healing in control group in 4th day (20%) and in 7th day (38%) was higher than
R Stricta group (P |
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| Keywords: Wound healing, Rhazya stricta, Phenytoin, Rat |
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Full-Text [PDF 3326 kb]
(3143 Downloads)
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Type of Study: Research |
Subject:
General
Received: 2009/01/25 | Published: 2000/05/15
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