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Proteomics Study of extremely low frequency electromagnetic field (50 Hz) on human neuroblastoma cells
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Hadi Hasanzadeh   , Mostafa Rezaie-Tavirani , Samaneh Seyyedi , Alireza Emadi |
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Abstract: (6030 Views) |
| Introduction: Extremely low frequency electromagnetic field (ELF-EMF) is one of common environmental factors in today’s modern life. In recent years, a special interest has been directed toward the possible effects of ELF-EMFs on biological systems. Since the mechanism underlying the ELF-EMFs’ biological effects are still unknown, we decided to conduct an in vitro study to understand the possible mechanisms.
Material and Methods: SH-SY5Y- human neuroblastoma cell line were placed in the EL-EM Field with the intensity of 1 mT and frequency of 50 Hz and for a period of 4 hours/day, in 2 days period. The cell morphology and protein expression were measured by using proteomic methods. Statistical analysis was performed by using Non Linear Spot Progenesis Same software.
Results : Our results showed that ELF-EMF could likely change the cell morphology and proliferation.
Conclusion: Statistical analysis in our study showed that ELF-EMF with a frequency of 50Hz and intensity of 1mT could significantly change the protein expression (P &le 0.05).
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| Keywords: Electromagnetic fields, Proteomics, Neuroblastoma |
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Full-Text [PDF 727 kb]
(1587 Downloads)
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Type of Study: Research |
Subject:
General
Received: 2015/08/11 | Accepted: 2015/09/7 | Published: 2015/09/26
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