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A rare case of Marshall syndrome
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Farhad ملک   , A. li Gohari |
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Abstract: (12869 Views) |
| Marshall syndrome includes periodic fever, aphthus ulcer,
pharyngitis and adenitis. This syndrome is known by recurrent fever and
pharyngitis. General lymphadenopathy is not common. The etiology is still
unknown. Disease onset is unually before the age of 5 years and generally
resolves by adolescence. During acute episodes white blood cell and erythrocyte
sedimentation rate are elevated. Fever lasts 3-6 days with a recurrence of symptoms every
3-8 weeks. Laboratory findings are normal until the next bout of fever .The
acute febrile symptomatic episodes can be treated by single doses of
prednisolone (1 to 2 mg/kg). In the past cimetidine was used for the treatment
of disease. Also colchicine was used for prophylaxis of fever attack. There is
controversy about tonsillectomy in the treatment of this syndrome. The disease
is self limiting and usually resolved without sequelae. This case report is about a 28 year old lady with
periodic fever and chills, pharyngitis and oral aphthus since 6 month prior to
admission with diagnosis of Marshall syndrome. Symptoms were resolved
dramatically after single dose of prednisolon. In the next attacks of fever,
treatment was done with the same drug. This report is important because this
syndrome is rare and due to unresponsive to current medication, its diagnosis
is necessary. |
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| Keywords: Marshall syndrome, Pharyngitis, Aphthous Stomatitis |
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Full-Text [PDF 149 kb]
(1781 Downloads)
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Type of Study: case report |
Subject:
General
Received: 2013/01/26 | Accepted: 2013/09/8 | Published: 2013/09/10
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