A 22-years-old presented with sever man pain in Costochondral region and mild fever, anorexia, sweating and weight-loss. He had history of consumption of non-pasteurized cheese. In physical examination patient was ill and diaphoretic, temperature 37.8˚c and severe tenderness in third right Costa chondral junction. STA for Brucella was positive (1/320). Patient treated with rifampin and doxycyclin. Constitutional symptoms subsided after 10 days but costochondral pain in 1 month. In endemic area patients with costochondritis also should evaluated for brucellosis