|
Long–term antibody response and immunologic memory in children immunized with hepatitis B vaccine at birth
|
M. J. صفار   , M. S. رضایی |
|
|
|
Abstract: (72070 Views) |
| Introduction: To evaluate the long-term immunity and immunologic memory provided by universal hepatitis B vaccination program at birth, and to evaluate the booster effects of different dosages of hepatitis B vaccine on children, who lost protective antibody titers to hepatitis B surface antigen (HBs – Ag), this study was conducted.
Methods: community-based sero-epidemiologic study was done on 453 healthy 10.5 years old Iranian children, one decade after implementation of a mass hepatitis B vaccination program. A booster vaccination with different dosages was given for children who did not have protective level of anti-hepatitis B surface antigen antibody (anti-HBs). Quantitative serologic responses to different dosages of vaccine were compared using X2 statistical test.
Results: A total of 42% children (191 of 453) children had low concentration ( |
|
| Keywords: Hepatitis B vaccine, Booster dose vaccination, Immunologic memory, Long-term immunity. |
|
|
Full-Text [PDF 220 kb]
(10526 Downloads)
|
Type of Study: Applicable |
Subject:
General
Received: 2008/09/14 | Published: 2004/02/15
|
|
|
|
|
|
|
| Send email to the article author |
|
|
|
| Add your comments about this article |
|
|
|
