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Starvation and antimetabolic therapy promote cytokine release and recruitment of immune cells. Proc Natl Acad Sci 2020; 117: 9932-9941. [ DOI:10.1073/pnas.1913707117] [ PMID] [ PMCID] 22. [22] Zou MX, Peng AB, Lv GH, Wang XB, Li J, She XL, Jiang Y. Expression of programmed death-1 ligand (PD-L1) in tumor-infiltrating lymphocytes is associated with favorable spinal chordoma prognosis. Am J Transl Res 2016; 8: 3274 23. [1] Dai H, Wang Y, Lu X, Han W. Chimeric antigen receptors modified T-cells for cancer therapy. J Natl Cancer Inst 2016; 108. [ DOI:10.1093/jnci/djv439] [ PMID] [ PMCID] 24. [2] Petersdorf EW. Role of major histocompatibility complex variation in graft-versus-host disease after hematopoietic cell transplantation. F1000Res 2017; 6: 617. [ DOI:10.12688/f1000research.10990.1] [ PMID] [ PMCID] 25. [3] Pakos‐Zebrucka K. Koryga I, Mnich K, Ljujic M, Samali A, Gorman AM. The integrated stress response. EMBO Rep 2016; 17: 1374-1395. [ DOI:10.15252/embr.201642195] [ PMID] [ PMCID] 26. [4] Costa-Mattioli M, Walter P. The integrated stress response: From mechanism to disease. Science 2020; 80: 368. [ DOI:10.1126/science.aat5314] [ PMID] 27. [5] Klassen J. The role of photopheresis in the treatment of graft-versus-host disease. Curr Oncol 2010; 17: 55. [ DOI:10.3747/co.v17i2.565] [ PMID] [ PMCID] 28. [6] Borzoueisileh S, Monfared AS, Abediankenari S, Mostafazadeh A. The assessment of cytotoxic T cell and natural killer cells activity in residents of high and ordinary background radiation areas of Ramsar-Iran. J Med Phys Assoc Med Phys India 2013; 38: 30. [ DOI:10.4103/0971-6203.106602] [ PMID] [ PMCID] 29. [7] Borzoueisileh S, Monfared AS, Abediankenari S, Mostafazadeh A, Khosravifarsani M, Amiri M, Elahimanesh F. The comparison of CD4/CD8 ratio among high and ordinary background radiation areas in Ramsar, Iran. Int J Low Radiat 2011; 8: 329-337. [ DOI:10.1504/IJLR.2011.046531] 30. [8] Shin JT, Opalenik SR, Wehby JN, Mahesh VK, Jackson A, Tarantini F, et al. Serum-starvation induces the extracellular appearance of FGF-1. Biochim Biophys Acta (BBA)-Mol Cell Res 1996; 1312: 27-38. [ DOI:10.1016/0167-4889(96)00013-4] 31. [9] Vasudevan S, Steitz JA. AU-rich-element-mediated upregulation of translation by FXR1 and Argonaute 2. Cell 2007; 128: 1105-1118. [ DOI:10.1016/j.cell.2007.01.038] [ PMID] [ PMCID] 32. [10] González-Polo RA, Boya P, Pauleau AL, Jalil A, Larochette N, Souquère S, et al. The apoptosis/autophagy paradox: autophagic vacuolization before apoptotic death. J Cell Sci 2005; 118: 3091-3102. [ DOI:10.1242/jcs.02447] [ PMID] 33. [11] Ni P, Xu H, Chen C, Wang J, Liu X, Hu Y, et al. Serum starvation induces DRAM expression in liver cancer cells via histone modifications within its promoter locus. PLoS One 2012; 7: e50502. [ DOI:10.1371/journal.pone.0050502] [ PMID] [ PMCID] 34. [12] Chen M, Huang J, Yang X, Liu B, Zhang W, Huang L, et al. Serum starvation induced cell cycle synchronization facilitates human somatic cells reprogramming. PLoS One 2012; 7: e28203. [ DOI:10.1371/journal.pone.0028203] [ PMID] [ PMCID] 35. [13] Britain CM, Dorsett KA, Bellis SL. The glycosyltransferase ST6Gal-I protects tumor cells against serum growth factor withdrawal by enhancing survival signaling and proliferative potential. J Biol Chem 2017; 292: 4663-4673. [ DOI:10.1074/jbc.M116.763862] [ PMID] [ PMCID] 36. [14] Tian X, Huang B, Zhang XP, Lu M, Liu F, Onuchic JN, Wang W. Modeling the response of a tumor-suppressive network to mitogenic and oncogenic signals. Proc Natl Acad Sci 2017; 114: 5337-5342. [ DOI:10.1073/pnas.1702412114] [ PMID] [ PMCID] 37. [15] Rahmani M, Khorasani HR, Golpour M, Shabestani Monfared A, Nattaj H, Abedian S, Mostafazadeh A. Stable down-regulation of HLA class-I by serum starvation in human PBMCs. Iran J Immunol 2016; 13: 54-63. (Persian). 38. [16] Rahmani M, Mohammadnia-Afrouzi M, Nouri HR, Fattahi S, Akhavan-Niaki H, Mostafazadeh A. Human PBMCs fight or flight response to starvation stress: Increased T-reg, FOXP3, and TGF-β1 with decreased miR-21 and Constant miR-181c levels, Biomed. Pharmacother 2018; 108: 1404-1411. [ DOI:10.1016/j.biopha.2018.09.163] [ PMID] 39. [17] Nami S, Aghebati-Maleki A, Babaloo Z, Aghebati-Maleki L. Effects of fasting on the immune system function and its positive effects on the chemotherapy of various types of cancer. Koomesh 2020; 22: 404-410. (Persian) [ DOI:10.29252/koomesh.22.3.404] 40. [18] Kandoi S, Patra B, Vidyasekar P, Sivanesan D, Vijayalakshmi S, Rajagopal K, Verma RS. Evaluation of platelet lysate as a substitute for FBS in explant and enzymatic isolation methods of human umbilical cord MSCs. Sci Rep 2018; 8: 1-12. [ DOI:10.1038/s41598-018-30772-4] [ PMID] [ PMCID] 41. [19] Smith C, Miles JJ, Khanna R. Advances in direct T‐cell alloreactivity: function, avidity, biophysics and structure. Am J Transplant 2012; 12: 15-26. [ DOI:10.1111/j.1600-6143.2011.03863.x] [ PMID] 42. [20] Dong Y, Sun Q, Zhang X. PD-1 and its ligands are important immune checkpoints in cancer. Oncotarget 2017; 8: 2171. [ DOI:10.18632/oncotarget.13895] [ PMID] [ PMCID] 43. [21] Püschel F, Favaro F, Redondo-Pedraza J, Lucendo E, Iurlaro R, Marchetti S, et al. Starvation and antimetabolic therapy promote cytokine release and recruitment of immune cells. Proc Natl Acad Sci 2020; 117: 9932-9941. [ DOI:10.1073/pnas.1913707117] [ PMID] [ PMCID] 44. [22] Zou MX, Peng AB, Lv GH, Wang XB, Li J, She XL, Jiang Y. Expression of programmed death-1 ligand (PD-L1) in tumor-infiltrating lymphocytes is associated with favorable spinal chordoma prognosis. Am J Transl Res 2016; 8: 3274
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