Introduction: Mastalgia is a common complaint among women that requires proper medical treatment. The aim of this study was to investigate the comparison of fluoxetine versus tamoxifen effects on the mastalgia.
Materials and Methods: In this clinical trial, 62 women, who referred to surgical clinic of Rafsanjan Ali-Ibn Abi-Talib hospital in 2017, with a complaint of breast pain were selected and treated with fluoxetine or tamoxifen. Correspondingly, informed consent, demographic checklists and the visual scale of the pain were completed in pre-treatment and then 4, 8 and 12 weeks after the treatment.
Results: There was no significant difference between two groups in body mass index, duration of illness and duration of pain (P>0.05). Both fluoxetine and tamoxifen significantly reduced pain (P0.05).
Conclusion: Both fluoxetine and tamoxifen were equally effective as alternative therapies against mastalgia
Taghizadeh M, Elahabadi I, Kamiab Z, Zaydabadi Nejad N, Mortazavi Lahijani M, Vazirinejad R et al . A comparative study on the effects of fluoxetine and tamoxifen on the treatment of mastalgia: A randomized clinical trial. Koomesh 1399; 22 (4) :574-580 URL: http://koomeshjournal.semums.ac.ir/article-1-5823-en.html