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Relationship between shiftwork with hypercholesterolemia in Isfahan’s Mobarakeh Steel Company staff using random effects and marginalized random effects models
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Roghayyeh Hassanzadeh   , Anoshirvan Kazemnejad , Farid Zayeri |
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Abstract: (4045 Views) |
| Introduction: Disorders of blood lipids (Dislipidemia) are one of the most important risk factors for cardiovascular disease. Due to the high prevalence of impaired blood lipids, it is important to identify the factors that affect this health issue. Some researchers believe that shifting the cholesterol in the industrial sector has a role to play. The purpose of this study was to investigate the relationship between shifting and high cholesterol in employees of Mobarakeh Steel Company in Isfahan (Iran).
Materials and Methods: This historical cohort study was conducted on 7677 male staff of Isfahan’s Mobarakeh Steel Company during 2005 – 2015. The data was gathered using the recorded information in the periodic medical examination files. In this study, we fitted usual random intercept and the marginalized random intercept models for assessing the effect of shiftwork on hypercholesterolemia. Correspondingly, estimaties were adjusted for age, body mass index (BMI) and smoking status. Finally, the goodness of fit indices for these models was compared. Statistical analyses were performed using the SAS software version 9.3 and R software version 2.8.1.
Results: A total of 7677 staff including 4372 (56.9%) shiftworker and 2429 (31.6%) hypercholesterolemia was studied. After adjusting for age, body mass index (BMI) and smoking status, we found no significant relationship between shiftwork and hypercholesterolemia, using both the random effects and marginalized random effects models. In Random effects model age (P |
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| Keywords: Shiftwork Schedule, Hypercholesterolemia, Statistical Models, Random Effects Model |
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Full-Text [PDF 1252 kb]
(720 Downloads)
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Type of Study: Research |
Subject:
General
Received: 2017/05/9 | Accepted: 2018/03/7 | Published: 2018/09/23
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