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:: Volume 19, Issue 4 ( (پياپی 68)، پائیز 1396) ::
Koomesh 1396, 19(4): 735-741 Back to browse issues page
Investigation of blood levels of vitamin D in women with breast cancer and its correlation with prognostic markers
Vahid Semnani , Ensieh Farhidzadeh , Majid Mirmohammadkhani , Farahnaz Ghahremanfard
Abstract:   (4832 Views)
Introduction: Breast cancer is the most common cancer among women and the second cause of death after lung cancer. Several studies have been conducted to find the better prognosis in patients with breast cancer, which have associated with contradictory results. Current study was done in order to find the relationship between vitamin D and tumor markers and to improve the prognosis of breast cancer patients Materials and Methods: In this cross-sectional descriptive-analytic study, 105 patients referred to oncology clinics of Fatemieh and Kowsar hospitals in Semnan city (Iran) from 2012 to 2016 years were evaluated.  Levels of vitamin D, prognostic markers of breast cancer including estrogen, progesterone, HER-2, P53 and Cyclin D1 receptors and menopause status of patients and also relationship between them were assessed. Results: The results showed that mean of vitamin D was optimal (22.8±9.48) and the maximum frequency of markers related to ER and PR and the minimum one related to HER2. There was not statistically significant relationships between markers and level of vitamin D, but menopausal status and the level of vitamin D had a significant relationship, so that the level of vitamin D in menopausal women was higher than non-menopausal women (p
Keywords: Breast Cancer, Tumor Marker, Vitamin D, Menopause.
Full-Text [PDF 570 kb]   (1146 Downloads)    
Type of Study: Research | Subject: General
Received: 2016/10/24 | Accepted: 2017/08/9 | Published: 2017/10/2
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Semnani V, Farhidzadeh E, Mirmohammadkhani M, Ghahremanfard F. Investigation of blood levels of vitamin D in women with breast cancer and its correlation with prognostic markers . Koomesh 1396; 19 (4) :735-741
URL: http://koomeshjournal.semums.ac.ir/article-1-3686-en.html


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Volume 19, Issue 4 ( (پياپی 68)، پائیز 1396) Back to browse issues page
کومش Koomesh
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