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:: Volume 19, Issue 3 (لد 19، شماره 3 (پياپی 67)، تابستان 1396 1396) ::
Koomesh 1396, 19(3): 515-522 Back to browse issues page
Role of adiponectin in patients with end-stage renal failure
Sara Beigrezaei , Maryam Heidari , Mohammad Reza Tamadon
Abstract:   (5546 Views)
Adiponectin is a cytokine produced by the adipose tissue. This collagen-like protein has 244-amino acid and its concentration in plasma of healthy individuals is 5-40 μg / mL. In fact, adiponectin comprises 1% of the total serum protein.  Although, adiponectin has anti-inflammatory and anti-atherogenic effects in physiological conditions and plays a key role in lipid and glucose metabolism and energy balance as well. However, in patients with end-stage renal disease, it is not a protector due to the changes in the structure and function, and also is considered as a risk factor. So with regard to the prevalence of atherosclerosis in patients with end stage renal disease, adiponectin may be a marker for indentifying the cardiovascular involvement of these patients.
Keywords: Adiponectin, Atherosclerosis, Kidney Diseases, Cardiovascular Diseases, Adipose Tissue
Full-Text [PDF 575 kb]   (2171 Downloads)    
Type of Study: Review | Subject: General
Received: 2016/09/14 | Accepted: 2017/03/27 | Published: 2017/06/21
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Beigrezaei S, Heidari M, Tamadon M R. Role of adiponectin in patients with end-stage renal failure. Koomesh 1396; 19 (3) :515-522
URL: http://koomeshjournal.semums.ac.ir/article-1-3565-en.html


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Volume 19, Issue 3 (لد 19، شماره 3 (پياپی 67)، تابستان 1396 1396) Back to browse issues page
کومش Koomesh
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