اکثر مکاتبات کومش از طریق ایمیل سایت می باشد. لطفا Spam ایمیل خود را نیز چک نمایید.
   [Home ] [Archive]   [ فارسی ]  
:: ::
:: Volume 17, Issue 2 (جلد 17 (2). پياپی (58). زمستان 1394 1394) ::
Koomesh 1394, 17(2): 518-531 Back to browse issues page
Production and optimization of kojic acid by locally isolated fungi Aspergillus sp. using response surface methodology
Mahdi Shahriarinour *, Farid Azizi Jalilian, Hossein Ali Safakhah
Abstract:   (5356 Views)
Introduction: Kojic acid with the chemical structure of 5-hydroxy-2-hydroxymethyl-ˠ-Piron is an organic acid that is biologically produced through aerobic fermentation process by using various substrates and via the function of variety of fungi. This study was aimed to study the optimization of Kojic acid production by Locally Isolated Fungi Aspergillus sp., using ‘Response Surface Methodology’. Materials and Methods: Kojic acid was produced by fermentation of isolated strain of genus Aspergillus in submerged culture medium. Initial investigation in Kojic acid  production process was performed via Plackett-Burman method and by using different nitrogen sources such as yeast extract, peptone, ammonium sulfate, ammonium chloride, urea as well as different carbon sources, including fructose, sucrose, glucose, lactose and maltose. Results: Based on our study, peptone and glucose were the most effective factors with carbon and nitrogen sources in production of kojic acid (P
Keywords: Kojic Acid, Optimization, Aspergillus
Full-Text [PDF 1686 kb]   (1914 Downloads)    
Type of Study: Research | Subject: General
Received: 2015/08/10 | Accepted: 2015/12/13 | Published: 2015/12/16
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

shahriarinour M, Azizi Jalilian F, Safakhah H A. Production and optimization of kojic acid by locally isolated fungi Aspergillus sp. using response surface methodology. Koomesh 1394; 17 (2) :518-531
URL: http://koomeshjournal.semums.ac.ir/article-1-2984-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 17, Issue 2 (جلد 17 (2). پياپی (58). زمستان 1394 1394) Back to browse issues page
کومش Koomesh
Persian site map - English site map - Created in 0.05 seconds with 30 queries by YEKTAWEB 4514