|
Synthesis of ZnO:Mg nanoparticle with sol-gel method and its antimicrobial efficacy against Listeria Monocytogenes PTCC 1294 (Serotype 1a)
|
Nima Shadan   , Khosro Issazadeh , Mahdi ShahriariNour , A. li Abdolahzadeh , Fared Azizi jalilian , Hadi Hasanzadeh , Sona Dalilan |
|
|
|
Abstract: (7587 Views) |
| Introduction: Listeria monocytogenes is the disease agent of listeriosis and creates primary
meningitis, septicemia and food poisoning in due to consumption dairy in
adults. In pregnant women usually causesbacterimia that lead to inflammation of
the placenta, fetal infection and eventually abortion. Since today strains of L.monocytogenes
have progressivily become resistant to various antibiotics and the
antimicrobial materials, this makes it necessary to synthesize the nanopaticle
which have antimicrobial effects. Purpose of this study was also to synthesize
ZnO nanoparticle with magnesium doping (ZnO:Mg) and investigate its inhibitory effect
on L.monocytogenes. Materials and Methods: ZnO:Mg
nanoparticle were prepared and synthesized using Sol-Gel method in Atomic
Percents of 1%, 3%, 5%, 7%. Tests of XRD
and transmission electron microscopy performed in order to study the structure
of the nanoparticle and evaluation its quality and also measurement of Optical density
and scanning electron microscopy was used to study antimicrobial effect of
nanoparticle. Results: The results obtained from measurement of optical density and
scanning electron microscopy showed that depending on the parameters of
nanoparticle dilutions, atomic percent, temperature and duration, the amount of
bacteria colonies has been significantly and mainly decreased and inhibited. Conclusion: Due to the growing trend of drug resistance,
suitable structural characteristics and purity crystalline nanoparticles ZnO:Mg,
it can be inoculated, particularly in atomic percentages of 5% and 7% for the inhibition
and destruction of L.monocytogenes. |
|
| Keywords: ZnO nanoparticle, Mg, Listeria monocytogenes, Sol-Gel Method, Optical Density |
|
|
Full-Text [PDF 1544 kb]
(3147 Downloads)
|
Type of Study: Research |
Subject:
General
Received: 2014/06/14 | Accepted: 2014/10/22 | Published: 2014/12/15
|
|
|
|
|
|
|
| Send email to the article author |
|
|
|
| Add your comments about this article |
|
|
|
