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Incidence of post operative nausea and vomiting following induction and maintance of general anesthesia with propofol or induction by propofol and maintenance with isoflurane: A randomized clinical trial
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Babak Hosseinzadeh   , Fatemeh Zahedian , Raheb Ghorbani , Mohammad Forozesfard |
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Abstract: (11673 Views) |
| Introduction: Post operative nausea and vomiting (PONV) are one of the most common
complications after surgery. One possible way for the solution of this problem
is using a suitable drug for anesthesia. Propofol decreases the rate of PONV.
As we know, no study used propofol as a single drug for general anesthesia.
Thus, the aim of this study was to compare the incidence of PONV following
anesthesia induction and maintenance by propofol with anesthesia induction by
propofol and maintenance by isoflurane. Materials and Methods: In this clinical trial, 196 patients with ASA (American Society of
Anesthesiologists) class I and II aged from 16 to 65 years old who were
candidates for general, orthopedic and urology surgeries were chosen. The
patients were randomly divided into two 98 person groups. In group A, propofol
was used for induction and maintenance of anesthesia and in group B propofol
and isoflurane were used for induction and maintenance of anesthesia,
respectively. The incidence of PONV was
recorded at 1 and 6 hours after the surgery. Results: The incidence of PONV in group A (propofol) was significantly lower than
group B (propofol + isoflurane) in the first six hours after surgery. Conclusion: Our findings show that in comparison with propofol + isoflurane, using
propofol for both induction and maintenance of anesthesia significantly
decrease the incidence of PONV after general, orthopedic and urology surgeries. |
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| Keywords: General anesthesia, Postoperative nausea and vomiting, propofol, Inhalation anesthetics, Postoperative complications |
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Full-Text [PDF 269 kb]
(3355 Downloads)
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Type of Study: Research |
Subject:
General
Received: 2012/09/23 | Accepted: 2013/09/8 | Published: 2013/09/10
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