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:: Volume 14, Issue 1 ((پياپي 45)، پائيز 1391) ::
Koomesh 1391, 14(1): 33-38 Back to browse issues page
Similar efficacy of vancomycin and teicoplanin in treatment of catheter related infection in hemodialysis patients
Mohamad Reza Tamadon , Alireza Soliemani , Malihe Yarmohamadi , Vahid سمنانی , Raheb قربانی , Farhad ملک , Mojtaba ملک
Abstract:   (19972 Views)
  Introduction: Catheter related infection is one of the most important complications of vascular access devices. Treatment of these complications is important and life saving. The most common causative organisms are gram-positive bacteria especially staphylococcus. Vancomycin and teicoplanin are two antibiotics which widely used for invasive beta-lactam-resistant Gram-positive infections. In this study, we aimed to compare efficacy of vancomycin and teicoplanin in treatment of catheter related infection.   Material and Methods: In this clinical trial, 43 patients with catheter infection were enrolled. Diagnosis was based on clinical criteria. 22 patients were received teicoplanin 800mg intra-venous loading dose and 400mg at days 2th, 3th,5th,12th,19th and 21 patients received vancomycin 1gr intra venous loading dose and 500mg every 5 days and for 3 weeks. A criterion for treatment response was absence of fever after 72 hours.   Results: %57.1 patients who received vancomycin and %68.2 patients who received teicoplanin had clinical response (p=0.454). In patients who received vancomycin, one case developed red man syndrome and one case developed diarrhea (9.5%) and in tiecoplanin group one patient developed rash (9.1%). Conclusion: Our findings show that there is no significant difference between two groups in treatment of catheter related infection in hemodialysis patients
Keywords: Teicoplanin, Vancomycin, Catheter-related infections, Renal dialysis
Full-Text [PDF 189 kb]   (2199 Downloads)    
Type of Study: Research | Subject: General
Received: 2012/01/9 | Published: 2012/09/15
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Tamadon M R, Soliemani A, Yarmohamadi M, سمنانی V, قربانی R, ملک F et al . Similar efficacy of vancomycin and teicoplanin in treatment of catheter related infection in hemodialysis patients. Koomesh 1391; 14 (1) :33-38
URL: http://koomeshjournal.semums.ac.ir/article-1-1608-en.html


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Volume 14, Issue 1 ((پياپي 45)، پائيز 1391) Back to browse issues page
کومش Koomesh
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